The darkness environment dramatically alters the chemistry of the brain, manifesting especially in neuro-endocrine systems which govern consciousness and regulate body functions. An important neurotransmitter involved in waking consciousness (seratonin) converts into a regulatory hormone (melatonin) that shuts down the organ systems, quieting the body in preparation for the finer and subtler realities of higher consciousness. The pineal gland initiates a cascade of inhibitory reactions, permitting visions and dream-states to emerge in our conscious awareness. Eventually, the brain synthesizes the "spirit-molecules" 5-methoxy-dimenthyltryptamine (5-MeO-DMT) and dimethyltryptamine (DMT), facilitating the transcendental experiences of universal love and compassion.